SNL’s official twitter account announced the news on Thursday evening (24 September). The post also revealed that rapper Megan Thee Stallion will feature as a musical guest on the first episode.
This will be Rock’s third appearance as an SNL host, having previously emceed the show in 1996 and 2014.
The comedian was also a cast member for three years between 1990 and 1993, and has since made various cameo appearances over the years.
After halting production in March due to pandemic-related filming restrictions, SNL concluded its previous season by airing three remotely-produced episodes.
The popular show will return to live broadcasts on 3 October for its 46th series.
Earlier this week, Bridesmaids star Maya Rudolph won an Emmy for her performance as Biden’s running mate Kamala Harris on the hit sketch show.